From your peers

Get the lowdown directly from your peers! Read on to find out how scientists just like you are resolving their protein research.

 

iCE

  • iCE3 kicks method development into high gear at Cook Pharmica"The short run times and easy sample preparation allowed for method development within a day or two. The versatility of the instrument allows the possibility of offering clients rapid alternatives to traditional ID and charge heterogeneity assays."

    - Joan Garrison, QC Method Transfer Scientist, Cook Pharmica

 

MFI

  • MFI Raises the Bar on Product Quality for KBI Biopharma Clients"We’re able to do extended analysis with images provided by MFI and then bridge this data with other techniques to identify and rapidly classify particles in solution. This helps our clients understand their products better and ensure they are providing the highest quality product to their patients."

    - Amber Fradkin, Ph.D., Associate Director, Particle Characterization Core Facility, KBI Biopharma
  • MFI + Bot1 a slam-dunk for biosimilars analysis at Samsung"As a biosimilar company, we investigate whether our products are similar to reference material, and use the MFI to perform comparability and stability. We must test samples from a variety of sources... for all these samples, we chose the automated MFI with Bot1 because a manual-only system just wouldn't have enough throughput."

    - Yuhwa Lee, Research Engineer, Samsung Bioepis

 

Simple Plex

  • Ella Speeds Up the Transition of Pediatric Sepsis Biomarkers from Validation to the Clinic at the University of Toronto"Ella allows us to rapidly quantify biomarkers from hundreds of cryopreserved samples and correlate them to specific outcomes. Now we’re ready to validate that what we identified in frozen plasma samples correlates to fresh blood samples taken at the point-of-care. Ella’s simplicity and reproducibility will allow us to reliably test samples across different sites, enhancing triage especially in remote locations of developing countries where access to trained healthcare professionals is unlikely."

    - Aleks Leligdowicz, M.D./Ph.D., Department of Medicine, University of Toronto
  • Yale University Fast-tracks Detection of Viral Responses During Pregnancy with Ella"Simple Plex assays on Ella gave us speed and efficiency so we could complete our assays quickly, and the high quality of the data meant that we could easily see differences between disease state samples and controls. Plus, sample preparation was so simple it reduced chances of errors significantly."

    - Paulomi Aldo, Research Associate and Reproductive Sciences Core Manager, Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University

 

Simple Western

  • Wes Speeds Up the Core at Xavier University of Louisiana"We’ve been able to increase productivity dramatically with Wes. The results are much better too, given that it removes the blotting step all together."

    - Melyssa Bratton, Ph.D., Manager of the Cell, Molecular, and Biostatistics Core, Xavier University of Louisiana
  • Wes Takes on Far-Western Blotting to Detect Protein Phosphorylation at UConn Health"The no-gel, no-transfer, no-membrane features are beneficial for the reproducibility of the assay. I really like this system over traditional Western."

    - Kazuya Machida, M.D., Ph.D., Associate Professor, Department of Genetics and Genome Sciences, UConn Health
  • Getting to Better Outcomes for Osteoarthritis Patients with Wes at the University of Chester"Wes gives me more throughput so I can get more replicates and trust my results a little bit more, and I can trust them straight away rather than having to do a lot of repeats. And obviously I like getting results the same day rather than having to wait two days"

    - Emma Wilson (née Humphrey), Ph.D., Lecturer in Molecular Biology, Institute of Medicine, University of Chester
  • Making the Link Between Obesity and Cancer with the NanoPro 1000 at Roseman University of Health Sciences"The Simple Western Charge assay, a capillary isoelectric focusing immunoassay, exceeded the reliability of 2D Western blots for resolving recombinant PKG-Iα and PKG-Iβ and uses 100,000X less sample quantity, making it well-suited for clinical disease proteomics because protein isoforms and post-translational modifications can be detected in precious tissue biopsies."

    - Mary G. Johlfs, M.S., Director of Research Operations/Scientist, Roseman University of Health Sciences
  • Wes is Keeping Things Green at the University of Alberta"The traditional blotting method can use up to 300 pieces of plastic and Wes uses two. What's even better is that Wes can run up to 40 proteins in three days. It would take about a week to run 40 proteins using Western blotting."

    - Jamie Boisvenue, Cardiovascular Research Technician, Department of Pediatrics, University of Alberta Faculty of Medicine & Dentistry
  • Wes Cuts Time to Results and Solves the Membrane Protein Challenge at the University of Nevada School of Medicine"We had been trying to study receptor proteins with traditional Westerns but it was frustrating—we just could not get it. A few months with Wes and we've already had way more success than we had in three years."

    - Brian Perrino, Ph.D., Associate Professor, Department of Physiology and Cell Biology, University of Nevada School of Medicine
  • Wes sets a new pace for Alzheimer's research at the University of Texas Health Science Center"The rapid, reproducible results on small amounts of tissue/cell lysates have allowed me to generate a more thorough data set on additional proteins, samples, conditions and brain regions all in the same amount, or even less time, as traditional Western blot. This technology has made it possible for small research labs to compete with the pace that research is conducted in large labs or companies."

    - Miranda Orr, Ph.D., Postdoctoral Fellow, University of Texas Health Science Center
  • Wes ups the data points count on laser capture microdissection samples at East Tennessee State University"We collect samples from laser microdissection and were using our entire sample on just one regular Western blot. With Wes, we can do multiple assays with one sample collection."

    - Mary Howell, Laboratory Coordinator, Department of Internal Medicine, East Tennessee State University
  • Wes changes the brain receptor research game at the University of Texas"One of the best advantages of using Wes is that it saves a lot of time, both in terms of hands-on time and in time to completion of the experiment. We were spending more than 4 hours of hands-on time per Western blot with traditional methods, and we can set up a run on the Wes in about 45 minutes. Our Wes runs are completed in less than 4 hours, as opposed to 4 days with traditional methods."

    - Noelle Anastasio, Ph.D., Assistant Professor, Department of Pharmacology and Toxicology, University of Texas Medical Branch