Maurice S.

IgG purity and heterogeneity

Maurice S. simplifies your size separations workflow by cutting out all the optimization guesswork. His ready-to-go CE-SDS cartridge gives you IgG purity data in 35 minutes. The best part? Get method development done in a day—platform methods too! Now you can run all your antibodies to get the purity data, heavy and light chain content and HC vs. NGHC composition you need.

Maurice S.

He simplifies your CE-SDS workflow by removing all the set-up and optimization guesswork—it's all done in his ready-to-go cartridge! So you can get purity and heterogeneity data on your mAbs, in 35 minutes. The best part? Method development is such a breeze.

How Can Maurice S. Help You?

I have many samples and my schedule is tight

Maurice S. produces size-based CE-SDS data in 35 minutes. The fast separation time, flexible workflow and high reproducibility makes Maurice S. a true lab workhorse. In one day you can complete your method development, or analyze 48 to 100 samples in one batch. The icing? You can develop platform methods and use them for multiple molecules too.

My current method is not reproducible and error-prone

Maurice S. employs a prequalified, ready-to-use cartridge design which fully automates column conditioning and clean up. No laborious capillary assembly or maintenance is required.

I work in a GMP lab and data integrity is key to my compliance requirement

Compass for iCE, the software package Maurice S. uses to acquire, manage and analyze data, has all the tools required for 21 CFR compliance so you'll have no issue analyzing biotherapeutics on Maurice in a regulated environment.

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Specifications
FEATURE CE-SDS SPECIFICATION
Minimum Sample Volume 50 µL
Sample Delivery Electrokinetic
Typical Separation Time Reduced IgG: 25 min, Non-reduced IgG: 35 min
Detection Capability UV Absorbance at 220 nm
Typical Voltage Separation: 5750 V
Sample Injections per Cartridge 100 guaranteed, 200 maximum
Maximum Sample Injections per Batch 48
Size Range 10–240 kDa
Sizing CV ≤2%
Relative Migration Time CV <1% for reduced IgG
Sizing Resolution ≥1.5 for NGHC/HC IgG Standard
Dynamic Range 2 logs
Linearity >0.995
Sensitivity (LOD) 0.3 µg/mL
(Value based on Internal Standard)
Sample Tray Options 96-well plates or 48 vials